Our approach to using data

Our approach to using data

How we use summary statistics from GWAS

Genomics plc believes that analysis across many, integrated, genotype-phenotype studies has the potential to revolutionise healthcare. We are working to bring such datasets together in a way that allows comprehensive analysis to elucidate important aspects of human biology, particularly with respect to health and disease. In collaboration with our partners, we will use these analyses to derive new insights into their research programmes and help them make better decisions.

We are integrating data from a variety of sources, with an important component being summary statistics from genome-wide association studies (i.e. effect size estimates, confidence intervals, p-values, and the positions in the genome of genetic variants). We also generate our own summary statistics from individual level genetic data. We take legal, ethical and security issues extremely seriously and, in all cases, we will respect any terms and conditions that apply to our use of any data. Read more about our information security standards here.

In keeping with standard practices, we will never share individual-level data unless there is a clear, permitted process for doing so. We will also never simply redistribute others’ summary statistic data en masse; rather, we seek to generate scientific and commercial value by conducting our own novel analyses across these data.

So far, scientists on behalf of over 220 institutions worldwide (listed below) have contributed summary statistics to this effort. We are grateful to these scientists and their research funders and are happy to acknowledge them here, and in our other publications.

We believe that the sharing and widespread use of these data will accelerate scientific research to help improve the treatment of human disease.

Academia Sinica, Taiwan
Addenbrooke’s Hospital, UK
Aravind Medical Research Foundation, India
Azienda Ospedaliero-Universitaria Careggi of Florence, Italy
Beaumont Hospital, Ireland
Boston Children’s Hospital, USA
Boston University, USA
Brigham and Women’s Hospital, USA
Broad Institute of MIT and Harvard University, USA
Brown University, USA
Cambridge University Hospitals, UK
Cancer Prevention Institute of California, USA
Capital Medical University, China
Cardiff University, UK
Casa Sollievo della Sofferenza Research Hospital, Italy
Case Western Reserve University, USA
Cedars Sinai Medical Center, USA
Centers for Disease Control and Prevention, USA
Centre for Medical Sytems Biology, Netherlands
Centre National de Génotypage, France
Cervello Hospital, Italy
Chiba University, Japan
Children’s Hospital of Philadelphia, USA
Chinese Academy of Medical Sciences, China
Chinese University of Hong Kong, China
Churchill Hospital, UK
Cincinnati Children’s Hospital Medical Research Center, USA
Columbia University, USA
Cornell University, USA
Dalhousie University, Canada
Dana-Farber Cancer Institute, USA
Dana-Farber/Boston Children’s Hospital Cancer and Blood Disorders Center, USA
Dartmouth College, USA
Duke University, USA
École Polytechnique Fédérale de Lausanne, France
EMGO+ Institute for Health and Care Research, Netherlands
Erasmus Medical Center, Netherlands
Erasmus University Rotterdam, Netherlands
European Academy Bozen/Bolzano, Italy
Flinders Medical Centre, Australia
Fondation Jean-Dausset- Centre d’Etude du Polymorphisme Humain, France
Fred Hutchinson Cancer Research Center, USA
Freiburg University Hospital, Germany
Fremantle Hospital, Australia
Fujian Medical University, China
General Central Hospital, Italy
Geneva University Hospital, Switzerland
Genome Institute of Singapore, Singapore
Georgetown University, USA
German Cancer Research Center, Germany
German Center for Diabetes Research, Germany
German Center for Neurodegenerative Diseases, Germany
German Research Center for Environmental Health, Germany
Glenfield Hospital, UK
Groningen University, Netherlands
Group Health Cooperative, USA
Harvard University, USA
Hospital for Special Surgery, USA
Hua Shan Hospital at Fudan University, China
Icelandic Heart Association, Iceland
Imperial College London, UK
Indiana University, USA
Institut National de la Santé et la Recherche Médicale, France
Institute of Genetic and Biomedical Research, Italy
Institute of Metabolic Science, UK
Institute Pasteur de Lille, France
IRCCS Istituto Auxologico Italiano, Italy
IRCCS-CSS Hospital, Italy
Istituto di Ricerche Farmacologiche Mario Negri, Italy
Johns Hopkins University, USA
Karolinska Institutet, Sweden
Kiel University, Germany
King Faisal Specialist Hospital and Research Centre, Saudi Arabia
King Saud University, Saudi Arabia
King’s College London, UK
Kyoto Prefectural University of Medicine, Japan
Leiden University Medical Center, Netherlands
Lille University, France
Lund University, Sweden
Massachusetts General Hospital, USA
Mater Health Services, Australia
Max Planck Institute of Experimental Medicine, Germany
Max Planck Institute of Psychiatry, Germany
Mayo Clinic, USA
McGill University, Canada
Medical Research Foundation, India
Monell Chemical Senses Center, USA
Montreal Heart Institute, Canada
Mount Sinai School of Medicine, USA
National Blood Service, UK
National Cancer Institute, USA
National Eye Institute, USA
National Health Research Institutes, Taiwan
National Health Service (NHS) Blood and Transplant, UK
National Heart Lung and Blood Institute, USA
National Human Genome Research Institute, Finland
National Institute for Health and Welfare, USA
National Institute of Allergy and Infectious Diseases, USA
National Institute of Arthritis and Musculoskeletal and Skin Diseases, USA
National Institute of Diabetes and Digestive and Kidney Diseases, USA
National Institute of Mental Health, USA
National Institute of Neurological Disorders and Stroke, USA
National Institute on Aging, USA
National Institute on Minority Health and Health Disparities, Netherlands
National Institutes of Health, USA
National Society for Epilepsy, UK
National University of Singapore, Singapore
Nemours Alfred I. duPont Hospital for Children, USA
New York University, USA
Newcastle University, UK
North Carolina State University, USA
NorthShore University HealthSystem, USA
Northumbria University, UK
Ohio State Medical Center, USA
Oklahoma Medical Research Foundation, USA
Orebro University Hospital, Sweden
Partners Center for Personalized Genetic Medicine, USA
Pierre and Marie Curie University, France
Queen Mary University of London, UK
Queensland Institute of Medical Research, Australia
Queensland University of Technology, Australia
Research Institute for Industrial Economics, Sweden
RIKEN, Japan
Royal Adelaide Hospital, Australia
Royal Brisbane and Women’s Hospital, Australia
Royal College of Surgeons in Ireland, Ireland
Ruijin Hospital, China
Rutgers University, USA
Shandong Academy of Medical Science, China
Shandong Center for Disease Control and Prevention, China
Skåne University Hosptial, Sweden
Sloan-Kettering Institute, USA
Stanford University, USA
Statens Serum Institut, Denmark
SUNY Upstate Medical University, USA
Swiss Institute of Bioinformatics, Switzerland
Technical University of Denmark, Denmark
Texas Biomedical Research Institute, USA
The Hospital for Sick Children, Canada
Townsville Hospital, Australia
Trinity College, Dublin, Ireland
Umeå University, Sweden
Universidad de Granada, Spain
Università degli Studi di Milano, Italy
Universität Münster, Germany
Université de Montréal, Canada
University College London, UK
University Health Network, Canada
University Hospital “Sestre Milosrdnice”, Croatia
University Hospital Careggi of Florence, Italy
University Hospital Dresden, Germany
University Hospital of Lille and Nancy, France
University Hospital Regensburg, Germany
University Medical Center Groningen, Netherlands
University Medical Center Utrecht, Netherlands
University Medicine Greifswald, Germany
University of Alabama at Birmingham, USA
University of Amsterdam, Netherlands
University of Bonn, Germany
University of Bristol, UK
University of California at Los Angeles, USA
University of California San Francisco, USA
University of Cambridge, UK
University of Chicago, USA
University of Colorado Denver, USA
University of Copenhagen, Denmark
University of Eastern Finland, Finland
University of Edinburgh, UK
University of Exeter, UK
University of Florida, USA
University of Geneva, Switzerland
University of Gothenburg, Sweden
University of Groningen, Spain
University of Hawaii, Netherlands
University of Helsinki, USA
University of Iceland, Iceland
University of Ioannina, Greece
University of Lausanne, Switzerland
University of Leicester, UK
University of Leuven, Belgium
University of Louisville, UK
University of Lubeck, USA
University of Manchester, Germany
University of Maryland, USA
University of Miami, USA
University of Michigan, USA
University of Minnesota, USA
University of North Carolina, USA
University of Nottingham, UK
University of Otago, New Zealand
University of Oulu, Finland
University of Oxford, UK
University of Padua, Italy
University of Pennsylvania, USA
University of Pittsburgh, USA
University of Queensland, Australia
University of Regensburg, Germany
University of Sheffield, UK
University of Southern California, USA
University of Split, Croatia
University of Surrey, UK
University of Tartu, Estonia
University of Tennessee, USA
University of Texas, USA
University of Tokyo, Japan
University of Toronto, Canada
University of Trento, Italy
University of Utah, USA
University of Vermont, USA
University of Virginia, USA
University of Washington, USA
University Schleswig-Holstein, Germany
Uppsala University, Sweden
VA Boston Healthcare System, USA
Vanderbilt University, USA
Vietnam National Institute of Ophthalmology, Vietnam
Virginia Commonwealth University, USA
Vrije Universiteit Amsterdam, Netherlands
Wake Forest University, USA
Washington DC VA Medical Center, USA
Washington University in St. Louis, USA
Weill Cornell Medical College, USA
Weill Cornell Medicine‐Qatar, Qatar
Wellcome Trust Sanger Institute, UK
Xinxiang Medical University, China
Zhengzhou University, China